![]() ![]() Thrombocytopenia is a condition in which the platelets (also called thrombocytes) are low in number, which can result in bleeding problems. If you're experiencing any symptoms following a COVID-19 vaccination, you can use the COVID-19 Vaccine Side Effect Checker. Mechanism action of platelets and crucial blood coagulation pathways in hemostasis.The AstraZeneca COVID-19 vaccine has been linked to a very rare blood-clotting disorder called 'thrombosis with thrombocytopenia syndrome’ (TTS). You can learn more about how we ensure our content is accurate and current by reading our editorial policy. We link primary sources - including studies, scientific references, and statistics - within each article and also list them in the resources section at the bottom of our articles. Medical News Today has strict sourcing guidelines and draws only from peer-reviewed studies, academic research institutions, and medical journals and associations. Aspiration involves the collection of a small amount of fluid, whereas a biopsy involves the collection of some soft tissue.Ī doctor may diagnose thrombocytopenia after ruling out other causes of a low platelet count. Both tests require a doctor to use a needle to take a sample of the bone marrow for examination. There are two types of bone marrow tests: a bone marrow aspiration and a bone marrow biopsy. other blood tests to assess blood clotting.a blood smear test, which involves looking at platelets under a microscope.The doctor is likely to perform other blood tests at the same time. The examination will assess for skin rashes and bruising.Ī laboratory platelet count will confirm the diagnosis, showing the exact concentration of platelets in the blood. The questions might cover symptoms, family history, and medications. To diagnose a low platelet count, a doctor may begin by asking some questions and performing a physical examination. sulfonamides, such as trimethoprim-sulfamethoxazole.seizure medications, such as carbamazepine.glycoprotein IIb/IIIa inhibitors, including abciximab, eptifibatide, and tirofiban.Prescription medications that can cause thrombocytopenia include: Over-the-counter (OTC) medications that can cause a low platelet count include: If the cause is a drug that a person is taking for a different condition, the prescribing doctor might change the medication. Doing so should return the platelet count to normal. If a substance is causing a person’s low platelet count, a doctor may suggest that they stop taking it. quinine, which is in tonic water and some tablets for leg cramps.poisonous substances, such as pesticides, arsenic, and benzene.Various substances can cause a person to have a low platelet count, including: Medications and substances that can cause a low platelet count ![]() The exact reason for this is unknown, but it seems to be more common close to delivery. Pregnancy may sometimes cause a person to develop mild thrombocytopenia. Surgery: In some cases, artificial heart valves, blood vessel grafts, or machines and tubing for blood transfusions or bypass surgery may destroy a person’s platelets.This can cause a low platelet count in the person’s blood. Large spleen: If a person’s spleen is large, it may store too many platelets.Infections: Bacterial or viral infections may lower a person’s platelet count temporarily.These conditions can cause the body to use up all of the available platelets, leading to a low platelet count. These conditions include thrombotic thrombocytopenic purpura (TTP) and disseminated intravascular coagulation (DIC). Conditions that cause blood clots: Some conditions cause blood clots to develop.Some cancer treatments, including radiation therapy and chemotherapy, may also destroy stem cells. This can cause the person’s stem cells to stop growing healthy blood cells. Cancer: Some cancers, such as leukemia or lymphoma, can damage a person’s bone marrow and destroy blood stem cells.Diseases that can do this include ITP, lupus, and rheumatoid arthritis. Autoimmune diseases : Certain autoimmune diseases can cause a person’s immune system to mistakenly attack and destroy their platelets.Aplastic anemia : This rare blood condition occurs when the bone marrow stops making an adequate number of new blood cells.the spleen holding onto too many platelets, meaning that the amount in the blood is too lowĬertain medical conditions can also cause a person to have a low platelet count.the body destroying or using up the platelets that the bone marrow does produce.the bone marrow not producing enough platelets.Medical conditions that can cause a low platelet count These factors can lower the platelet count by affecting the production, storage, use, or destruction of platelets. There are two main factors that cause a person to have a low platelet count: an underlying health condition or a medication. What are the causes of a low platelet count? ![]()
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